MLB PICKS

MLB Picks for May 26

ParlayLab's methodology engine grades the Tuesday, May 26, 2026 MLB slate against the market. 15 games with 4 HIGH-confidence picks — moneyline, run line, total, and player props. The full pick selections are available with a free 7-day Pro trial.

Los Angeles Angels at Detroit Tigers

6:40 PM ET

Angels (9-24) visit the Tigers (13-23). Probable starters: J. Kochanowicz (5.23) for Angels, K. Montero (3.68) for Tigers. Weather at first pitch: 79°F, 8 mph wind.

Pitchers

LAAJ. Kochanowicz (5.23)

DETK. Montero (3.68)

FanDuel lines

MLLAA · DET

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Chicago Cubs at Pittsburgh Pirates

6:40 PM ET

Cubs (20-15) visit the Pirates (17-18). Probable starters: J. Wicks (10.45) for Cubs, B. Ashcraft (3.49) for Pirates. Weather at first pitch: 82°F, 4 mph wind.

Pitchers

CHCJ. Wicks (10.45)

PITB. Ashcraft (3.49)

FanDuel lines

MLCHC · PIT

RL

Total

ParlayLab pick

HIGH

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Atlanta Braves at Boston Red Sox

6:45 PM ET

Braves (23-11) visit the Red Sox (16-18). Probable starters: S. Strider (4.00) for Braves, R. Suarez (2.94) for Red Sox. Weather at first pitch: 81°F, 12 mph wind.

Pitchers

ATLS. Strider (4.00)

BOSR. Suarez (2.94)

FanDuel lines

MLATL · BOS

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Miami Marlins at Toronto Blue Jays

7:07 PM ET

Marlins (17-18) visit the Blue Jays (18-19). Probable starters: S. Alcantara (4.00) for Marlins, B. Fisher (3.48) for Blue Jays. Dome — no weather impact.

Pitchers

MIAS. Alcantara (4.00)

TORB. Fisher (3.48)

FanDuel lines

MLMIA · TOR

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Cincinnati Reds at New York Mets

7:10 PM ET

Reds (18-16) visit the Mets (14-20). Probable starters: C. Burns (2.40) for Reds, D. Peterson (6.75) for Mets. Weather at first pitch: 70°F, 9 mph wind.

Pitchers

CINC. Burns (2.40)

NYMD. Peterson (6.75)

FanDuel lines

MLCIN · NYM

RL

Total

ParlayLab pick

HIGH

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Minnesota Twins at Chicago White Sox

7:40 PM ET

Twins (14-21) visit the White Sox (20-14). Probable starters: J. Ryan (2.85) for Twins, S. Burke (3.56) for White Sox. Weather at first pitch: 76°F, 4 mph wind.

Pitchers

MINJ. Ryan (2.85)

CWSS. Burke (3.56)

FanDuel lines

MLMIN · CWS

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

New York Yankees at Kansas City Royals

7:40 PM ET

Yankees (21-14) visit the Royals (14-21). Probable starters: C. Schlittler (2.01) for Yankees, B. Falter (13.97) for Royals. Weather at first pitch: 79°F, 7 mph wind.

Pitchers

NYYC. Schlittler (2.01)

KCB. Falter (13.97)

FanDuel lines

MLNYY · KC

RL

Total

ParlayLab pick

HIGH

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Houston Astros at Texas Rangers

8:05 PM ET

Astros (15-19) visit the Rangers (14-19). Probable starters: J. Alexander (9.33) for Astros, J. Leiter (4.86) for Rangers. Dome — no weather impact.

Pitchers

HOUJ. Alexander (9.33)

TEXJ. Leiter (4.86)

FanDuel lines

MLHOU · TEX

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Seattle Mariners at Athletics

9:40 PM ET

Mariners (17-18) visit the Athletics (18-18). Probable starters: E. Hancock (3.23) for Mariners, G. Jump (3.77) for Athletics. Weather at first pitch: 60°F, 12 mph wind.

Pitchers

SEAE. Hancock (3.23)

ATHG. Jump (3.77)

FanDuel lines

MLSEA · ATH

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

AZ at San Francisco Giants

9:45 PM ET

AZ (18-15) visit the Giants (15-19). Probable starters: E. Rodriguez (2.25) for AZ, T. Mahle (5.70) for Giants. Weather at first pitch: 59°F, 17 mph wind.

Pitchers

AZE. Rodriguez (2.25)

SFT. Mahle (5.70)

FanDuel lines

MLAZ · SF

RL

Total

ParlayLab pick

HIGH

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with a Pro trial. No card charged for the first 7 days.