MLB PICKS

MLB Picks for May 26

ParlayLab's methodology engine grades the Tuesday, May 26, 2026 MLB slate against the market. 15 games with 2 HIGH-confidence picks — moneyline, run line, total, and player props. The full pick selections are available with a free 7-day Pro trial.

Los Angeles Angels at Detroit Tigers

6:40 PM ET

Angels (9-24) visit the Tigers (13-23). Probable starters: J. Kochanowicz (4.55) for Angels, K. Montero (3.83) for Tigers. Weather at first pitch: 79°F.

Pitchers

LAAJ. Kochanowicz (4.55)

DETK. Montero (3.83)

FanDuel lines

MLLAA +116 · DET -134

RL+1.5

TotalO/U 8.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Chicago Cubs at Pittsburgh Pirates

6:40 PM ET

Cubs (20-15) visit the Pirates (17-18). Probable starters: J. Wicks (16.62) for Cubs, B. Ashcraft (2.89) for Pirates. Weather at first pitch: 82°F.

Pitchers

CHCJ. Wicks (16.62)

PITB. Ashcraft (2.89)

FanDuel lines

MLCHC +114 · PIT -134

RL+1.5

TotalO/U 8.5

ParlayLab pick

HIGH

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Atlanta Braves at Boston Red Sox

6:45 PM ET

Braves (23-11) visit the Red Sox (16-18). Probable starters: S. Strider (3.00) for Braves, R. Suarez (2.40) for Red Sox. Weather at first pitch: 81°F.

Pitchers

ATLS. Strider (3.00)

BOSR. Suarez (2.40)

FanDuel lines

MLATL -106 · BOS -110

RL-1.5

TotalO/U 8

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Miami Marlins at Toronto Blue Jays

7:07 PM ET

Marlins (17-18) visit the Blue Jays (18-19). Probable starters: S. Alcantara (4.00) for Marlins, B. Fisher (2.73) for Blue Jays. Dome — no weather impact.

Pitchers

MIAS. Alcantara (4.00)

TORB. Fisher (2.73)

FanDuel lines

MLMIA +136 · TOR -162

RL-1.5

TotalO/U 7.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Cincinnati Reds at New York Mets

7:10 PM ET

Reds (18-16) visit the Mets (14-20). Probable starters: C. Burns (1.83) for Reds, D. Peterson (5.03) for Mets. Weather at first pitch: 70°F.

Pitchers

CINC. Burns (1.83)

NYMD. Peterson (5.03)

FanDuel lines

MLCIN -120 · NYM +102

RL-1.5

TotalO/U 7.5

ParlayLab pick

HIGH

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Houston Astros at Texas Rangers

8:05 PM ET

Astros (15-19) visit the Rangers (14-19). Probable starters: J. Alexander (9.33) for Astros, J. Leiter (4.61) for Rangers. Dome — no weather impact.

Pitchers

HOUJ. Alexander (9.33)

TEXJ. Leiter (4.61)

FanDuel lines

MLHOU +114 · TEX -134

RL+1.5

TotalO/U 8

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Seattle Mariners at Athletics

9:40 PM ET

Mariners (17-18) visit the Athletics (18-18). Probable starters: E. Hancock (3.07) for Mariners, G. Jump (4.35) for Athletics. Weather at first pitch: 60°F.

Pitchers

SEAE. Hancock (3.07)

ATHG. Jump (4.35)

FanDuel lines

MLSEA -104 · ATH -112

RL-1.5

TotalO/U 9.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

AZ at San Francisco Giants

9:45 PM ET

AZ (18-15) visit the Giants (15-19). Probable starters: E. Rodriguez (2.24) for AZ, T. Mahle (6.10) for Giants. Weather at first pitch: 59°F.

Pitchers

AZE. Rodriguez (2.24)

SFT. Mahle (6.10)

FanDuel lines

MLAZ -106 · SF -110

RL-1.5

TotalO/U 8

ParlayLab pick

HIGH

MED edge

ML / RL / O-U projection

Unlock with Pro

3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with a Pro trial. No card charged for the first 7 days.