MLB PICKS
ParlayLab's methodology engine grades the Monday, May 25, 2026 MLB slate against the market. 13 games with 3 HIGH-confidence picks — moneyline, run line, total, and player props. The full pick selections are available with Pro.
Cubs (29-24) visit the Pirates (27-26). Probable starters: B. Brown (1.74) for Cubs, C. Mlodzinski (3.79) for Pirates. Weather at first pitch: 72°F.
Pitchers
CHCB. Brown (1.74)
PITC. Mlodzinski (3.79)
FanDuel lines
MLCHC — · PIT —
RL—
Total—
ParlayLab pick
MEDMED edge
ML / RL / O-U projection
3 qualifying picks across moneyline, run line, and totals.
Rays (34-16) visit the Orioles (23-30). Probable starters: S. McClanahan (3.10) for Rays, K. Bradish (3.70) for Orioles. Weather at first pitch: 70°F, 1 mph wind.
Pitchers
TBS. McClanahan (3.10)
BALK. Bradish (3.70)
FanDuel lines
MLTB — · BAL —
RL—
Total—
ParlayLab pick
MEDMED edge
ML / RL / O-U projection
3 qualifying picks across moneyline, run line, and totals.
Twins (26-27) visit the White Sox (26-26). Probable starters: Z. Matthews (4.58) for Twins, A. Kay (4.09) for White Sox. Weather at first pitch: 72°F.
Pitchers
MINZ. Matthews (4.58)
CWSA. Kay (4.09)
FanDuel lines
MLMIN — · CWS —
RL—
Total—
ParlayLab pick
MEDMED edge
ML / RL / O-U projection
3 qualifying picks across moneyline, run line, and totals.
Cardinals (29-22) visit the Brewers (30-20). Probable starters: M. Liberatore (5.44) for Cardinals, J. Misiorowski (1.68) for Brewers. Dome — no weather impact.
Pitchers
STLM. Liberatore (5.44)
MILJ. Misiorowski (1.68)
FanDuel lines
MLSTL — · MIL —
RL—
Total—
ParlayLab pick
MEDMED edge
ML / RL / O-U projection
3 qualifying picks across moneyline, run line, and totals.
Yankees (31-22) visit the Royals (22-31). Probable starters: W. Warren (4.39) for Yankees, M. Wacha (3.49) for Royals. Weather at first pitch: 72°F.
Pitchers
NYYW. Warren (4.39)
KCM. Wacha (3.49)
FanDuel lines
MLNYY — · KC —
RL—
Total—
ParlayLab pick
MEDMED edge
ML / RL / O-U projection
3 qualifying picks across moneyline, run line, and totals.
Reds (27-25) visit the Mets (22-31). Probable starters: N. Lodolo (5.04) for Reds, N. McLean (3.21) for Mets. Weather at first pitch: 72°F.
Pitchers
CINN. Lodolo (5.04)
NYMN. McLean (3.21)
FanDuel lines
MLCIN — · NYM —
RL—
Total—
ParlayLab pick
MEDMED edge
ML / RL / O-U projection
3 qualifying picks across moneyline, run line, and totals.
AZ (28-24) visit the Giants (22-31). Probable starters: M. Kelly (5.35) for AZ, L. Roupp (4.34) for Giants. Weather at first pitch: 72°F.
Pitchers
AZM. Kelly (5.35)
SFL. Roupp (4.34)
FanDuel lines
MLAZ — · SF —
RL—
Total—
ParlayLab pick
MEDMED edge
ML / RL / O-U projection
3 qualifying picks across moneyline, run line, and totals.
Nationals (27-27) visit the Guardians (32-23). Probable starters: P. Poulin (2.83) for Nationals, T. Bibee (3.97) for Guardians. Weather at first pitch: 72°F.
Pitchers
WSHP. Poulin (2.83)
CLET. Bibee (3.97)
FanDuel lines
MLWSH — · CLE —
RL—
Total—
ParlayLab pick
LOWMED edge
ML / RL / O-U projection
3 qualifying picks across moneyline, run line, and totals.
Phillies (26-27) visit the Padres (31-21). Probable starters: J. Luzardo (3.23) for Phillies, G. Canning (6.67) for Padres. Weather at first pitch: 72°F.
Pitchers
PHIJ. Luzardo (3.23)
SDG. Canning (6.67)
FanDuel lines
MLPHI — · SD —
RL—
Total—
ParlayLab pick
HIGHHIGH edge
ML / RL / O-U projection
3 qualifying picks across moneyline, run line, and totals.
Astros (23-31) visit the Rangers (24-28). Probable starters: T. Imai (5.32) for Astros, K. Rocker (4.41) for Rangers. Dome — no weather impact.
Pitchers
HOUT. Imai (5.32)
TEXK. Rocker (4.41)
FanDuel lines
MLHOU — · TEX —
RL—
Total—
ParlayLab pick
MEDMED edge
ML / RL / O-U projection
3 qualifying picks across moneyline, run line, and totals.
Marlins (25-29) visit the Blue Jays (25-28). Probable starters: J. Junk (4.21) for Marlins, T. Yesavage (3.73) for Blue Jays. Dome — no weather impact.
Pitchers
MIAJ. Junk (4.21)
TORT. Yesavage (3.73)
FanDuel lines
MLMIA — · TOR —
RL—
Total—
ParlayLab pick
MEDMED edge
ML / RL / O-U projection
3 qualifying picks across moneyline, run line, and totals.
Rockies (20-34) visit the Dodgers (33-20). Probable starters: T. Gordon (5.38) for Rockies, E. Sheehan (4.95) for Dodgers. Weather at first pitch: 72°F.
Pitchers
COLT. Gordon (5.38)
LADE. Sheehan (4.95)
FanDuel lines
MLCOL — · LAD —
RL—
Total—
ParlayLab pick
HIGHHIGH edge
ML / RL / O-U projection
3 qualifying picks across moneyline, run line, and totals.
Mariners (25-29) visit the Athletics (27-26). Probable starters: L. Castillo (5.19) for Mariners, A. Civale (4.92) for Athletics. Weather at first pitch: 72°F.
Pitchers
SEAL. Castillo (5.19)
ATHA. Civale (4.92)
FanDuel lines
MLSEA — · ATH —
RL—
Total—
ParlayLab pick
HIGHHIGH edge
ML / RL / O-U projection
3 qualifying picks across moneyline, run line, and totals.
Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.
Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.
Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with Pro. You're charged when you subscribe — cancel anytime.