MLB PICKS

MLB Picks for May 15

ParlayLab's methodology engine grades the Friday, May 15, 2026 MLB slate against the market. 15 games with 5 HIGH-confidence picks — moneyline, run line, total, and player props. The full pick selections are available with a free 7-day Pro trial.

Toronto Blue Jays at Detroit Tigers

6:45 PM ET

Blue Jays (12-14) visit the Tigers (11-15). Probable starters: T. Yesavage (2.25) for Blue Jays, B. Hanifee (1.59) for Tigers. Weather at first pitch: 69°F.

Pitchers

TORT. Yesavage (2.25)

DETB. Hanifee (1.59)

FanDuel lines

MLTOR -124 · DET +106

RL-1.5

TotalO/U 8

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Miami Marlins at Tampa Bay Rays

7:10 PM ET

Marlins (11-13) visit the Rays (18-7). Probable starters: J. Junk (4.81) for Marlins, I. Seymour (4.50) for Rays. Dome — no weather impact.

Pitchers

MIAJ. Junk (4.81)

TBI. Seymour (4.50)

FanDuel lines

MLMIA +102 · TB -120

RL+1.5

TotalO/U 7.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Boston Red Sox at Atlanta Braves

7:15 PM ET

Red Sox (12-13) visit the Braves (17-7). Probable starters: C. Early (3.33) for Red Sox, S. Strider (3.00) for Braves. Weather at first pitch: 77°F.

Pitchers

BOSC. Early (3.33)

ATLS. Strider (3.00)

FanDuel lines

MLBOS +118 · ATL -138

RL+1.5

TotalO/U 8

ParlayLab pick

MED

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

New York Yankees at New York Mets

7:15 PM ET

Yankees (16-9) visit the Mets (10-13). Probable starters: C. Schlittler (1.50) for Yankees, C. Holmes (1.86) for Mets. Weather at first pitch: 66°F.

Pitchers

NYYC. Schlittler (1.50)

NYMC. Holmes (1.86)

FanDuel lines

MLNYY -146 · NYM +124

RL-1.5

TotalO/U 7

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Chicago Cubs at Chicago White Sox

7:40 PM ET

Cubs (19-6) visit the White Sox (15-9). Probable starters: E. Cabrera (4.06) for Cubs, S. Burke (4.08) for White Sox. Weather at first pitch: 72°F.

Pitchers

CHCE. Cabrera (4.06)

CWSS. Burke (4.08)

FanDuel lines

MLCHC -126 · CWS +108

RL-1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Texas Rangers at Houston Astros

8:10 PM ET

Rangers (11-13) visit the Astros (8-16). Probable starters: J. Leiter (4.61) for Rangers, S. Arrighetti (1.32) for Astros. Dome — no weather impact.

Pitchers

TEXJ. Leiter (4.61)

HOUS. Arrighetti (1.32)

FanDuel lines

MLTEX -112 · HOU -104

RL-1.5

TotalO/U 8.5

ParlayLab pick

MED

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

AZ at Colorado Rockies

8:40 PM ET

AZ (9-13) visit the Rockies (10-15). Probable starters: M. Kelly (5.25) for AZ, K. Freeland (7.04) for Rockies. Weather at first pitch: 72°F.

Pitchers

AZM. Kelly (5.25)

COLK. Freeland (7.04)

FanDuel lines

MLAZ -122 · COL +104

RL-1.5

TotalO/U 11.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

San Diego Padres at Seattle Mariners

9:40 PM ET

Padres (13-11) visit the Mariners (13-12). Probable starters: R. Vásquez (2.96) for Padres, E. Hancock (3.07) for Mariners. Dome — no weather impact.

Pitchers

SDR. Vásquez (2.96)

SEAE. Hancock (3.07)

FanDuel lines

MLSD +114 · SEA -134

RL+1.5

TotalO/U 7

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

San Francisco Giants at Athletics

9:40 PM ET

Giants (11-13) visit the Athletics (13-12). Probable starters: T. Mahle (6.10) for Giants, A. Civale (3.31) for Athletics. Weather at first pitch: 58°F.

Pitchers

SFT. Mahle (6.10)

ATHA. Civale (3.31)

FanDuel lines

MLSF +110 · ATH -130

RL+1.5

TotalO/U 9.5

ParlayLab pick

MED

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with a Pro trial. No card charged for the first 7 days.