MLB PICKS

MLB Picks for May 10

ParlayLab's methodology engine grades the Sunday, May 10, 2026 MLB slate against the market. 15 games on the board — moneyline, run line, total, and player props. The full pick selections are available with Pro.

Washington Nationals at Miami Marlins

12:15 PM ET

Nationals (19-21) visit the Marlins (18-22). Probable starters: C. Cavalli (3.21) for Nationals, S. Alcantara (3.38) for Marlins. Dome — no weather impact.

Pitchers

WSHC. Cavalli (3.21)

MIAS. Alcantara (3.38)

FanDuel lines

MLWSH · MIA

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Athletics at Baltimore Orioles

1:35 PM ET

Athletics (21-18) visit the Orioles (17-23). Probable starters: L. Severino (4.23) for Athletics, K. Akin (5.68) for Orioles. Weather at first pitch: 83°F, 10 mph wind.

Pitchers

ATHL. Severino (4.23)

BALK. Akin (5.68)

FanDuel lines

MLATH · BAL

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Tampa Bay Rays at Boston Red Sox

1:35 PM ET

Rays (25-13) visit the Red Sox (17-22). Probable starters: N. Martinez (2.93) for Rays, P. Tolle (3.09) for Red Sox. Weather at first pitch: 67°F, 11 mph wind.

Pitchers

TBN. Martinez (2.93)

BOSP. Tolle (3.09)

FanDuel lines

MLTB · BOS

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Houston Astros at Cincinnati Reds

1:40 PM ET

Astros (16-24) visit the Reds (21-19). Probable starters: K. Teng (4.03) for Astros, A. Abbott (4.15) for Reds. Weather at first pitch: 72°F, 5 mph wind.

Pitchers

HOUK. Teng (4.03)

CINA. Abbott (4.15)

FanDuel lines

MLHOU · CIN

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Minnesota Twins at Cleveland Guardians

1:40 PM ET

Twins (17-23) visit the Guardians (21-20). Probable starters: A. Morris (3.82) for Twins, G. Williams (3.98) for Guardians. Weather at first pitch: 55°F, 7 mph wind.

Pitchers

MINA. Morris (3.82)

CLEG. Williams (3.98)

FanDuel lines

MLMIN · CLE

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Seattle Mariners at Chicago White Sox

2:10 PM ET

Mariners (19-21) visit the White Sox (18-21). Probable starters: L. Gilbert (3.36) for Mariners, D. Martin (4.17) for White Sox. Weather at first pitch: 60°F, 9 mph wind.

Pitchers

SEAL. Gilbert (3.36)

CWSD. Martin (4.17)

FanDuel lines

MLSEA · CWS

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Chicago Cubs at Texas Rangers

2:35 PM ET

Cubs (27-13) visit the Rangers (18-21). Probable starters: J. Taillon (5.96) for Cubs, J. deGrom (4.21) for Rangers. Dome — no weather impact.

Pitchers

CHCJ. Taillon (5.96)

TEXJ. deGrom (4.21)

FanDuel lines

MLCHC · TEX

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

New York Mets at AZ

4:10 PM ET

Mets (15-24) visit the AZ (18-20). Probable starters: H. Brazobán (1.73) for Mets, E. Rodriguez (2.50) for AZ. Weather at first pitch: 56°F, 17 mph wind.

Pitchers

NYMH. Brazobán (1.73)

AZE. Rodriguez (2.50)

FanDuel lines

MLNYM · AZ

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Atlanta Braves at Los Angeles Dodgers

4:10 PM ET

Braves (27-13) visit the Dodgers (24-15). Probable starters: B. Elder (3.95) for Braves, J. Wrobleski (3.44) for Dodgers. Weather at first pitch: 80°F, 8 mph wind.

Pitchers

ATLB. Elder (3.95)

LADJ. Wrobleski (3.44)

FanDuel lines

MLATL · LAD

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Detroit Tigers at Kansas City Royals

7:20 PM ET

Tigers (18-22) visit the Royals (19-21). Probable starters: B. Hanifee (5.06) for Tigers, N. Cameron (4.02) for Royals. Weather at first pitch: 72°F, 6 mph wind.

Pitchers

DETB. Hanifee (5.06)

KCN. Cameron (4.02)

FanDuel lines

MLDET · KC

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with Pro. You're charged when you subscribe — cancel anytime.