MLB PICKS

MLB Picks for May 6

ParlayLab's methodology engine grades the Wednesday, May 6, 2026 MLB slate against the market. 15 games on the board — moneyline, run line, total, and player props. The full pick selections are available with a free 7-day Pro trial.

Toronto Blue Jays at Tampa Bay Rays

1:10 PM ET

Blue Jays (9-11) visit the Rays (14-5). Probable starters: P. Corbin (4.73) for Blue Jays, S. McClanahan (3.05) for Rays. Dome — no weather impact.

Pitchers

TORP. Corbin (4.73)

TBS. McClanahan (3.05)

FanDuel lines

MLTOR · TB

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Los Angeles Dodgers at Houston Astros

2:10 PM ET

Dodgers (9-9) visit the Astros (6-11). Probable starters: T. Glasnow (2.56) for Dodgers, L. McCullers Jr. (6.86) for Astros. Dome — no weather impact.

Pitchers

LADT. Glasnow (2.56)

HOUL. McCullers Jr. (6.86)

FanDuel lines

MLLAD · HOU

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Chicago White Sox at Los Angeles Angels

4:07 PM ET

White Sox (11-7) visit the Angels (4-14). Probable starters: N. Schultz (6.00) for White Sox, W. Ureña (3.03) for Angels. Weather at first pitch: 72°F, 10 mph wind.

Pitchers

CWSN. Schultz (6.00)

LAAW. Ureña (3.03)

FanDuel lines

MLCWS · LAA

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Boston Red Sox at Detroit Tigers

6:40 PM ET

Red Sox (9-10) visit the Tigers (10-10). Probable starters: S. Gray (2.61) for Red Sox, J. Flaherty (4.60) for Tigers. Weather at first pitch: 53°F, 7 mph wind.

Pitchers

BOSS. Gray (2.61)

DETJ. Flaherty (4.60)

FanDuel lines

MLBOS · DET

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Athletics at Philadelphia Phillies

6:40 PM ET

Athletics (9-9) visit the Phillies (7-11). Probable starters: J. Springs (5.79) for Athletics, Z. Wheeler (2.28) for Phillies. Weather at first pitch: 66°F, 9 mph wind.

Pitchers

ATHJ. Springs (5.79)

PHIZ. Wheeler (2.28)

FanDuel lines

MLATH · PHI

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Texas Rangers at New York Yankees

7:05 PM ET

Rangers (7-10) visit the Yankees (15-3). Probable starters: N. Eovaldi (4.02) for Rangers, W. Warren (4.15) for Yankees. Weather at first pitch: 63°F, 5 mph wind.

Pitchers

TEXN. Eovaldi (4.02)

NYYW. Warren (4.15)

FanDuel lines

MLTEX · NYY

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Cincinnati Reds at Chicago Cubs

7:40 PM ET

Reds (10-8) visit the Cubs (15-3). Probable starters: B. Singer (5.03) for Reds, C. Rea (4.74) for Cubs. Weather at first pitch: 53°F, 12 mph wind.

Pitchers

CINB. Singer (5.03)

CHCC. Rea (4.74)

FanDuel lines

MLCIN · CHC

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

New York Mets at Colorado Rockies

9:20 PM ET

Mets (6-10) visit the Rockies (7-11). Probable starters: F. Peralta (4.68) for Mets, M. Lorenzen (6.46) for Rockies. Weather at first pitch: 37°F, 4 mph wind.

Pitchers

NYMF. Peralta (4.68)

COLM. Lorenzen (6.46)

FanDuel lines

MLNYM · COL

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Pittsburgh Pirates at AZ

9:40 PM ET

Pirates (9-9) visit the AZ (6-9). Probable starters: P. Skenes (3.58) for Pirates, M. Soroka (3.11) for AZ. Weather at first pitch: 57°F, 14 mph wind.

Pitchers

PITP. Skenes (3.58)

AZM. Soroka (3.11)

FanDuel lines

MLPIT · AZ

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with a Pro trial. No card charged for the first 7 days.