MLB PICKS

MLB Picks for May 5

ParlayLab's methodology engine grades the Tuesday, May 5, 2026 MLB slate against the market. 13 games on the board — moneyline, run line, total, and player props. The full pick selections are available with Pro.

Boston Red Sox at Detroit Tigers

6:40 PM ET

Red Sox (14-21) visit the Tigers (18-18). Probable starters: J. Morán (2.81) for Red Sox, F. Valdez (4.35) for Tigers. Weather at first pitch: 54°F, 4 mph wind.

Pitchers

BOSJ. Morán (2.81)

DETF. Valdez (4.35)

FanDuel lines

MLBOS · DET

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Toronto Blue Jays at Tampa Bay Rays

6:40 PM ET

Blue Jays (16-19) visit the Rays (22-12). Probable starters: K. Gausman (4.37) for Blue Jays, D. Rasmussen (2.95) for Rays. Dome — no weather impact.

Pitchers

TORK. Gausman (4.37)

TBD. Rasmussen (2.95)

FanDuel lines

MLTOR · TB

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Athletics at Philadelphia Phillies

6:40 PM ET

Athletics (18-16) visit the Phillies (15-20). Probable starters: L. Severino (4.23) for Athletics, C. Sánchez (2.62) for Phillies. Weather at first pitch: 78°F, 14 mph wind.

Pitchers

ATHL. Severino (4.23)

PHIC. Sánchez (2.62)

FanDuel lines

MLATH · PHI

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Baltimore Orioles at Miami Marlins

6:40 PM ET

Orioles (15-20) visit the Marlins (16-19). Probable starters: C. Bassitt (4.74) for Orioles, S. Alcantara (3.38) for Marlins. Dome — no weather impact.

Pitchers

BALC. Bassitt (4.74)

MIAS. Alcantara (3.38)

FanDuel lines

MLBAL · MIA

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Minnesota Twins at Washington Nationals

6:45 PM ET

Twins (15-20) visit the Nationals (16-19). Probable starters: T. Bradley (3.97) for Twins, C. Cavalli (3.21) for Nationals. Weather at first pitch: 79°F, 11 mph wind.

Pitchers

MINT. Bradley (3.97)

WSHC. Cavalli (3.21)

FanDuel lines

MLMIN · WSH

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Texas Rangers at New York Yankees

7:05 PM ET

Rangers (16-18) visit the Yankees (24-11). Probable starters: J. deGrom (4.21) for Rangers, E. Rodríguez (4.70) for Yankees. Weather at first pitch: 73°F, 12 mph wind.

Pitchers

TEXJ. deGrom (4.21)

NYYE. Rodríguez (4.70)

FanDuel lines

MLTEX · NYY

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Cincinnati Reds at Chicago Cubs

7:40 PM ET

Reds (20-15) visit the Cubs (23-12). Probable starters: A. Abbott (4.15) for Reds, J. Taillon (5.96) for Cubs. Weather at first pitch: 55°F, 6 mph wind.

Pitchers

CINA. Abbott (4.15)

CHCJ. Taillon (5.96)

FanDuel lines

MLCIN · CHC

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Chicago White Sox at Los Angeles Angels

9:38 PM ET

White Sox (17-18) visit the Angels (13-23). Probable starters: E. Fedde (4.18) for White Sox, S. Aldegheri (4.85) for Angels. Weather at first pitch: 64°F, 8 mph wind.

Pitchers

CWSE. Fedde (4.18)

LAAS. Aldegheri (4.85)

FanDuel lines

MLCWS · LAA

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Pittsburgh Pirates at AZ

9:40 PM ET

Pirates (19-16) visit the AZ (16-17). Probable starters: B. Chandler (4.38) for Pirates, E. Rodriguez (2.50) for AZ. Weather at first pitch: 56°F, 26 mph wind.

Pitchers

PITB. Chandler (4.38)

AZE. Rodriguez (2.50)

FanDuel lines

MLPIT · AZ

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with Pro. You're charged when you subscribe — cancel anytime.