MLB PICKS

MLB Picks for May 5

ParlayLab's methodology engine grades the Tuesday, May 5, 2026 MLB slate against the market. 13 games with 2 HIGH-confidence picks — moneyline, run line, total, and player props. The full pick selections are available with a free 7-day Pro trial.

Boston Red Sox at Detroit Tigers

6:40 PM ET

Red Sox (8-10) visit the Tigers (10-9). Probable starters: J. Morán (2.81) for Red Sox, F. Valdez (4.29) for Tigers. Weather at first pitch: 54°F, 4 mph wind.

Pitchers

BOSJ. Morán (2.81)

DETF. Valdez (4.29)

FanDuel lines

MLBOS · DET

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Toronto Blue Jays at Tampa Bay Rays

6:40 PM ET

Blue Jays (9-10) visit the Rays (13-5). Probable starters: K. Gausman (4.32) for Blue Jays, D. Rasmussen (2.78) for Rays. Dome — no weather impact.

Pitchers

TORK. Gausman (4.32)

TBD. Rasmussen (2.78)

FanDuel lines

MLTOR · TB

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Athletics at Philadelphia Phillies

6:40 PM ET

Athletics (9-8) visit the Phillies (6-11). Probable starters: L. Severino (4.23) for Athletics, C. Sánchez (2.62) for Phillies. Weather at first pitch: 78°F, 14 mph wind.

Pitchers

ATHL. Severino (4.23)

PHIC. Sánchez (2.62)

FanDuel lines

MLATH · PHI

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Baltimore Orioles at Miami Marlins

6:40 PM ET

Orioles (6-11) visit the Marlins (7-10). Probable starters: C. Bassitt (5.06) for Orioles, S. Alcantara (4.00) for Marlins. Dome — no weather impact.

Pitchers

BALC. Bassitt (5.06)

MIAS. Alcantara (4.00)

FanDuel lines

MLBAL · MIA

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Minnesota Twins at Washington Nationals

6:45 PM ET

Twins (4-13) visit the Nationals (8-10). Probable starters: T. Bradley (3.67) for Twins, C. Cavalli (3.88) for Nationals. Weather at first pitch: 79°F, 11 mph wind.

Pitchers

MINT. Bradley (3.67)

WSHC. Cavalli (3.88)

FanDuel lines

MLMIN · WSH

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Texas Rangers at New York Yankees

7:05 PM ET

Rangers (7-10) visit the Yankees (15-3). Probable starters: J. deGrom (3.48) for Rangers, E. Rodríguez (4.15) for Yankees. Weather at first pitch: 73°F, 12 mph wind.

Pitchers

TEXJ. deGrom (3.48)

NYYE. Rodríguez (4.15)

FanDuel lines

MLTEX · NYY

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Cincinnati Reds at Chicago Cubs

7:40 PM ET

Reds (10-8) visit the Cubs (15-3). Probable starters: A. Abbott (3.92) for Reds, J. Taillon (5.37) for Cubs. Weather at first pitch: 55°F, 6 mph wind.

Pitchers

CINA. Abbott (3.92)

CHCJ. Taillon (5.37)

FanDuel lines

MLCIN · CHC

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Chicago White Sox at Los Angeles Angels

9:38 PM ET

White Sox (11-7) visit the Angels (4-14). Probable starters: E. Fedde (4.34) for White Sox, S. Aldegheri (4.85) for Angels. Weather at first pitch: 64°F, 8 mph wind.

Pitchers

CWSE. Fedde (4.34)

LAAS. Aldegheri (4.85)

FanDuel lines

MLCWS · LAA

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Pittsburgh Pirates at AZ

9:40 PM ET

Pirates (9-9) visit the AZ (6-9). Probable starters: B. Chandler (4.82) for Pirates, E. Rodriguez (2.25) for AZ. Weather at first pitch: 56°F, 26 mph wind.

Pitchers

PITB. Chandler (4.82)

AZE. Rodriguez (2.25)

FanDuel lines

MLPIT · AZ

RL

Total

ParlayLab pick

LOW

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with a Pro trial. No card charged for the first 7 days.