MLB PICKS

MLB Picks for May 5

ParlayLab's methodology engine grades the Tuesday, May 5, 2026 MLB slate against the market. 14 games with 7 HIGH-confidence picks — moneyline, run line, total, and player props. The full pick selections are available with a free 7-day Pro trial.

Boston Red Sox at Detroit Tigers

6:40 PM ET

Red Sox (8-10) visit the Tigers (10-9). Probable starters: J. Morán (2.81) for Red Sox, F. Valdez (4.28) for Tigers. Weather at first pitch: 54°F.

Pitchers

BOSJ. Morán (2.81)

DETF. Valdez (4.28)

FanDuel lines

MLBOS +126 · DET -148

RL+1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Toronto Blue Jays at Tampa Bay Rays

6:40 PM ET

Blue Jays (9-10) visit the Rays (13-5). Probable starters: K. Gausman (3.23) for Blue Jays, D. Rasmussen (2.78) for Rays. Dome — no weather impact.

Pitchers

TORK. Gausman (3.23)

TBD. Rasmussen (2.78)

FanDuel lines

MLTOR +110 · TB -130

RL+1.5

TotalO/U 6.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Athletics at Philadelphia Phillies

6:40 PM ET

Athletics (9-8) visit the Phillies (6-11). Probable starters: L. Severino (4.23) for Athletics, C. Sánchez (1.62) for Phillies. Weather at first pitch: 78°F.

Pitchers

ATHL. Severino (4.23)

PHIC. Sánchez (1.62)

FanDuel lines

MLATH +140 · PHI -166

RL+1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Baltimore Orioles at Miami Marlins

6:40 PM ET

Orioles (6-11) visit the Marlins (7-10). Probable starters: C. Bassitt (5.51) for Orioles, S. Alcantara (4.00) for Marlins. Dome — no weather impact.

Pitchers

BALC. Bassitt (5.51)

MIAS. Alcantara (4.00)

FanDuel lines

MLBAL +122 · MIA -144

RL+1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Texas Rangers at New York Yankees

7:05 PM ET

Rangers (7-10) visit the Yankees (15-3). Probable starters: J. deGrom (3.86) for Rangers, E. Rodríguez (5.19) for Yankees. Weather at first pitch: 73°F.

Pitchers

TEXJ. deGrom (3.86)

NYYE. Rodríguez (5.19)

FanDuel lines

MLTEX +158 · NYY -188

RL+1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Cincinnati Reds at Chicago Cubs

7:40 PM ET

Reds (10-8) visit the Cubs (15-3). Probable starters: A. Abbott (3.97) for Reds, J. Taillon (5.20) for Cubs. Weather at first pitch: 55°F.

Pitchers

CINA. Abbott (3.97)

CHCJ. Taillon (5.20)

FanDuel lines

MLCIN +140 · CHC -166

RL+1.5

TotalO/U 8.5

ParlayLab pick

MED

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Pittsburgh Pirates at AZ

9:40 PM ET

Pirates (9-9) visit the AZ (6-9). Probable starters: B. Chandler (4.60) for Pirates, E. Rodriguez (2.24) for AZ. Weather at first pitch: 56°F.

Pitchers

PITB. Chandler (4.60)

AZE. Rodriguez (2.24)

FanDuel lines

MLPIT +114 · AZ -134

RL+1.5

TotalO/U 9

ParlayLab pick

LOW

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with a Pro trial. No card charged for the first 7 days.