MLB SLATE

MLB Slate for September 22

The slate for Tuesday, September 22, 2026 has 15 games, each with its probable starters, FanDuel lines, weather and ballpark. This slate came before the experimental MLB specialists began on September 30, 2026.

ParlayLab’s blanket moneyline, run-line and total picks were retired on September 30, 2026. MLB selections now come from 13 experimental specialists, decided before first pitch and logged at the price they were recorded at. See the specialists and their records.

Tampa Bay Rays at New York Yankees

1:05 PM ET

Rays (95-60) visit the Yankees (89-66). Probable starters: N. Martinez (3.10) for Rays, C. Rodón (2.67) for Yankees. Weather at first pitch: 66°F, 15 MPH wind.

Pitchers

TBN. Martinez (3.10)

NYYC. Rodón (2.67)

FanDuel Lines

MLTB +116 · NYY -134

RL+1.5

TotalO/U 7.5

MLB Specialists

Experimental

No specialist selection

Before the specialists began on Sep 30, 2026.

Research selections logged before first pitch, not betting-validated.

Tampa Bay Rays at New York Yankees

7:05 PM ET

Rays (95-60) visit the Yankees (89-66). Probable starters: D. Rasmussen (2.67) for Rays, M. Fried (2.80) for Yankees. Weather at first pitch: 64°F, 12 MPH wind.

Pitchers

TBD. Rasmussen (2.67)

NYYM. Fried (2.80)

FanDuel Lines

MLTB +110 · NYY -130

RL+1.5

TotalO/U 6.5

MLB Specialists

Experimental

No specialist selection

Before the specialists began on Sep 30, 2026.

Research selections logged before first pitch, not betting-validated.

Washington Nationals at Detroit Tigers

6:40 PM ET

Nationals (73-83) visit the Tigers (74-83). Probable starters: R. Cornelio (3.89) for Nationals, D. Anderson (3.67) for Tigers. Weather at first pitch: 60°F, 10 MPH wind.

Pitchers

WSHR. Cornelio (3.89)

DETD. Anderson (3.67)

FanDuel Lines

MLWSH +134 · DET -158

RL+1.5

TotalO/U 8.5

MLB Specialists

Experimental

No specialist selection

Before the specialists began on Sep 30, 2026.

Research selections logged before first pitch, not betting-validated.

St. Louis Cardinals at Pittsburgh Pirates

6:40 PM ET

Cardinals (74-79) visit the Pirates (78-76). Probable starters: A. Pallante (3.61) for Cardinals, J. Jones (3.87) for Pirates. Weather at first pitch: 58°F, 10 MPH wind.

Pitchers

STLA. Pallante (3.61)

PITJ. Jones (3.87)

FanDuel Lines

MLSTL +144 · PIT -172

RL+1.5

TotalO/U 7.5

MLB Specialists

Experimental

No specialist selection

Before the specialists began on Sep 30, 2026.

Research selections logged before first pitch, not betting-validated.

Milwaukee Brewers at Philadelphia Phillies

6:40 PM ET

Brewers (97-58) visit the Phillies (85-70). Probable starters: D. May (4.70) for Brewers, Z. Wheeler (3.06) for Phillies. Weather at first pitch: 62°F, 8 MPH wind.

Pitchers

MILD. May (4.70)

PHIZ. Wheeler (3.06)

FanDuel Lines

MLMIL +120 · PHI -142

RL+1.5

TotalO/U 7.5

MLB Specialists

Experimental

No specialist selection

Before the specialists began on Sep 30, 2026.

Research selections logged before first pitch, not betting-validated.

Cleveland Guardians at Boston Red Sox

6:45 PM ET

Guardians (80-75) visit the Red Sox (83-72). Probable starters: P. Messick (2.56) for Guardians, P. Tolle (3.03) for Red Sox. Weather at first pitch: 56°F, 6 MPH wind.

Pitchers

CLEP. Messick (2.56)

BOSP. Tolle (3.03)

FanDuel Lines

MLCLE +110 · BOS -130

RL+1.5

TotalO/U 6.5

MLB Specialists

Experimental

No specialist selection

Before the specialists began on Sep 30, 2026.

Research selections logged before first pitch, not betting-validated.

Cincinnati Reds at Atlanta Braves

7:15 PM ET

Reds (72-84) visit the Braves (92-64). Probable starters: B. Williamson (4.89) for Reds, J. Ritchie (4.79) for Braves. Weather at first pitch: 83°F, 7 MPH wind.

Pitchers

CINB. Williamson (4.89)

ATLJ. Ritchie (4.79)

FanDuel Lines

MLCIN +154 · ATL -184

RL+1.5

TotalO/U 9.5

MLB Specialists

Experimental

No specialist selection

Before the specialists began on Sep 30, 2026.

Research selections logged before first pitch, not betting-validated.

Chicago White Sox at Kansas City Royals

7:40 PM ET

White Sox (80-76) visit the Royals (67-88). Probable starters: A. Kay (4.44) for White Sox, D. Lynch IV (4.13) for Royals. Weather at first pitch: 66°F, 8 MPH wind.

Pitchers

CWSA. Kay (4.44)

KCD. Lynch IV (4.13)

FanDuel Lines

MLCWS -118 · KC +100

RL-1.5

TotalO/U 7.5

MLB Specialists

Experimental

No specialist selection

Before the specialists began on Sep 30, 2026.

Research selections logged before first pitch, not betting-validated.

Miami Marlins at Chicago Cubs

7:40 PM ET

Marlins (75-80) visit the Cubs (87-68). Probable starters: J. Junk (4.31) for Marlins, S. Imanaga (3.74) for Cubs. Weather at first pitch: 59°F, 14 MPH wind.

Pitchers

MIAJ. Junk (4.31)

CHCS. Imanaga (3.74)

FanDuel Lines

MLMIA +168 · CHC -200

RL+1.5

TotalO/U 6.5

MLB Specialists

Experimental

No specialist selection

Before the specialists began on Sep 30, 2026.

Research selections logged before first pitch, not betting-validated.

New York Mets at Texas Rangers

8:05 PM ET

Mets (71-85) visit the Rangers (77-77). Probable starters: S. Manaea (4.67) for Mets, M. Gore (4.59) for Rangers. Dome — no weather impact.

Pitchers

NYMS. Manaea (4.67)

TEXM. Gore (4.59)

FanDuel Lines

MLNYM +110 · TEX -130

RL+1.5

TotalO/U 8.5

MLB Specialists

Experimental

No specialist selection

Before the specialists began on Sep 30, 2026.

Research selections logged before first pitch, not betting-validated.

Arizona Diamondbacks at Colorado Rockies

8:40 PM ET

Diamondbacks (81-73) visit the Rockies (57-97). Probable starters: M. Soroka (3.31) for Diamondbacks, K. Freeland (6.58) for Rockies. Weather at first pitch: 74°F, 6 MPH wind.

Pitchers

AZM. Soroka (3.31)

COLK. Freeland (6.58)

FanDuel Lines

MLAZ -194 · COL +162

RL-1.5

TotalO/U 10.5

MLB Specialists

Experimental

No specialist selection

Before the specialists began on Sep 30, 2026.

Research selections logged before first pitch, not betting-validated.

Los Angeles Angels at Athletics

9:40 PM ET

Angels (58-93) visit the Athletics (58-95). Probable starters: Y. Kikuchi (4.88) for Angels, B. Basso (5.36) for Athletics. Weather at first pitch: 66°F, 30 MPH wind.

Pitchers

LAAY. Kikuchi (4.88)

ATHB. Basso (5.36)

FanDuel Lines

MLLAA -108 · ATH -108

RL-1.5

TotalO/U 9.5

MLB Specialists

Experimental

No specialist selection

Before the specialists began on Sep 30, 2026.

Research selections logged before first pitch, not betting-validated.

Houston Astros at Seattle Mariners

9:40 PM ET

Astros (77-79) visit the Mariners (72-80). Probable starters: C. Javier (5.14) for Astros, L. Gilbert (3.81) for Mariners. Dome — no weather impact.

Pitchers

HOUC. Javier (5.14)

SEAL. Gilbert (3.81)

FanDuel Lines

MLHOU +120 · SEA -142

RL+1.5

TotalO/U 7.5

MLB Specialists

Experimental

No specialist selection

Before the specialists began on Sep 30, 2026.

Research selections logged before first pitch, not betting-validated.

Minnesota Twins at San Francisco Giants

9:45 PM ET

Twins (73-83) visit the Giants (65-90). Probable starters: T. Bradley (3.81) for Twins, A. Molina (3.97) for Giants. Weather at first pitch: 59°F, 14 MPH wind.

Pitchers

MINT. Bradley (3.81)

SFA. Molina (3.97)

FanDuel Lines

MLMIN -134 · SF +114

RL-1.5

TotalO/U 7.5

MLB Specialists

Experimental

No specialist selection

Before the specialists began on Sep 30, 2026.

Research selections logged before first pitch, not betting-validated.

San Diego Padres at Los Angeles Dodgers

10:10 PM ET

Padres (85-68) visit the Dodgers (91-56). Probable starters: M. King (3.21) for Padres, B. Stewart (2.70) for Dodgers. Weather at first pitch: 69°F, 6 MPH wind.

Pitchers

SDM. King (3.21)

LADB. Stewart (2.70)

FanDuel Lines

MLSD +106 · LAD -124

RL+1.5

TotalO/U 8.5

MLB Specialists

Experimental

No specialist selection

Before the specialists began on Sep 30, 2026.

Research selections logged before first pitch, not betting-validated.

How ParlayLab Covers the Slate

Every MLB game carries its research: both starting pitchers’ season and recent form, the bullpens, each lineup against the hand it faces, ballpark factors, weather (wind relative to center field, temperature, precipitation), and the FanDuel moneyline, run line and total with their movement since the open.

Game selections come from 13 experimental MLB specialists — eight on the moneyline, two on the run line and three on the under. Each is a fixed rule on season-to-date team or starting-pitcher history, decided in the hour before first pitch and logged at the FanDuel price it was recorded at. They cover regular-season games only. Their historical records are exploratory backtests, not validated profitability and not live results, and a game none of them selects reads “No specialist selection”.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-versus-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-versus-line edges show up bright green; weak ones drop to orange or red.

Free users see the slate, the per-game matchup context shown above and the top props. The specialists’ tickets, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with Pro. You're charged when you subscribe — cancel anytime.