MLB PICKS

MLB Picks for August 22

ParlayLab's methodology engine grades the Saturday, August 22, 2026 MLB slate against the market. 15 games with 1 HIGH-confidence pick — moneyline, run line, total, and player props. The full pick selections are available with Pro.

Los Angeles Angels at Texas Rangers

7:05 PM ET

Angels (50-77) visit the Rangers (63-64). Probable starters: R. Johnson (5.17) for Angels, C. Bradford (4.45) for Rangers. Dome — no weather impact.

Pitchers

LAAR. Johnson (5.17)

TEXC. Bradford (4.45)

FanDuel lines

MLLAA +152 · TEX -166

RL+1.5

TotalO/U 8

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Atlanta Braves at Milwaukee Brewers

2:10 PM ET

Braves (75-54) visit the Brewers (79-49). Probable starters: M. Pérez (3.05) for Braves, L. Henderson (2.48) for Brewers. Dome — no weather impact.

Pitchers

ATLM. Pérez (3.05)

MILL. Henderson (2.48)

FanDuel lines

MLATL +144 · MIL -156

RL+1.5

TotalO/U 7.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

New York Mets at Chicago White Sox

7:10 PM ET

Mets (58-71) visit the White Sox (67-61). Probable starters: C. Scott (3.73) for Mets, L. Castillo (5.31) for White Sox. Weather at first pitch: 77°F, 12 mph wind.

Pitchers

NYMC. Scott (3.73)

CWSL. Castillo (5.31)

FanDuel lines

MLNYM +102 · CWS -110

RL-1.5

TotalO/U 8.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Cincinnati Reds at AZ

8:10 PM ET

Reds (61-68) visit the AZ (68-61). Probable starters: R. Lowder (5.14) for Reds, M. Soroka (2.93) for AZ. Weather at first pitch: 73°F, 8 mph wind.

Pitchers

CINR. Lowder (5.14)

AZM. Soroka (2.93)

FanDuel lines

MLCIN +170 · AZ -184

RL+1.5

TotalO/U 8

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Toronto Blue Jays at New York Yankees

1:35 PM ET

Blue Jays (63-67) visit the Yankees (73-55). Probable starters: D. Cease (2.33) for Blue Jays, R. Weathers (3.56) for Yankees. Weather at first pitch: 75°F, 9 mph wind.

Pitchers

TORD. Cease (2.33)

NYYR. Weathers (3.56)

FanDuel lines

MLTOR -104 · NYY -104

RL-1.5

TotalO/U 6.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Tampa Bay Rays at Baltimore Orioles

7:05 PM ET

Rays (76-52) visit the Orioles (62-67). Probable starters: S. McClanahan (3.19) for Rays, B. Young (3.38) for Orioles. Weather at first pitch: 74°F, 4 mph wind.

Pitchers

TBS. McClanahan (3.19)

BALB. Young (3.38)

FanDuel lines

MLTB -126 · BAL +116

RL-1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Athletics at Houston Astros

7:10 PM ET

Athletics (49-80) visit the Astros (65-64). Probable starters: J. Lopez (4.82) for Athletics, H. Brown (3.31) for Astros. Dome — no weather impact.

Pitchers

ATHJ. Lopez (4.82)

HOUH. Brown (3.31)

FanDuel lines

MLATH +215 · HOU -235

RL+1.5

TotalO/U 8

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Detroit Tigers at Kansas City Royals

7:15 PM ET

Tigers (61-67) visit the Royals (56-73). Probable starters: D. Anderson (3.73) for Tigers, M. Wacha (3.32) for Royals. Weather at first pitch: 83°F, 6 mph wind.

Pitchers

DETD. Anderson (3.73)

KCM. Wacha (3.32)

FanDuel lines

MLDET -104 · KC -104

RL-1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Chicago Cubs at Seattle Mariners

7:15 PM ET

Cubs (74-54) visit the Mariners (60-67). Probable starters: D. Peterson (5.11) for Cubs, K. Anderson (4.50) for Mariners. Dome — no weather impact.

Pitchers

CHCD. Peterson (5.11)

SEAK. Anderson (4.50)

FanDuel lines

MLCHC +106 · SEA -114

RL+1.5

TotalO/U 7.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

San Francisco Giants at Boston Red Sox

7:15 PM ET

Giants (52-76) visit the Red Sox (68-59). Probable starters: B. Tidwell (4.43) for Giants, P. Sandoval (4.41) for Red Sox. Weather at first pitch: 69°F, 7 mph wind.

Pitchers

SFB. Tidwell (4.43)

BOSP. Sandoval (4.41)

FanDuel lines

MLSF +186 · BOS -205

RL+1.5

TotalO/U 8

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Cleveland Guardians at Colorado Rockies

8:10 PM ET

Guardians (63-66) visit the Rockies (50-77). Probable starters: T. Bibee (3.88) for Guardians, G. Hughes (6.19) for Rockies. Weather at first pitch: 81°F, 7 mph wind.

Pitchers

CLET. Bibee (3.88)

COLG. Hughes (6.19)

FanDuel lines

MLCLE -132 · COL +122

RL-1.5

TotalO/U 10.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Minnesota Twins at San Diego Padres

8:40 PM ET

Twins (63-66) visit the Padres (68-60). Probable starters: D. Kremer (5.60) for Twins, C. Mize (3.45) for Padres. Weather at first pitch: 80°F, 5 mph wind.

Pitchers

MIND. Kremer (5.60)

SDC. Mize (3.45)

FanDuel lines

MLMIN +128 · SD -138

RL+1.5

TotalO/U 8

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with Pro. You're charged when you subscribe — cancel anytime.