MLB PICKS

MLB Picks for June 22

ParlayLab's methodology engine grades the Monday, June 22, 2026 MLB slate against the market. 12 games with 4 HIGH-confidence picks — moneyline, run line, total, and player props. The full pick selections are available with Pro.

New York Yankees at Detroit Tigers

6:10 PM ET

Yankees (46-30) visit the Tigers (33-44). Probable starters: G. Cole (3.19) for Yankees, F. Valdez (4.35) for Tigers. Weather at first pitch: 72°F, 8 mph wind.

Pitchers

NYYG. Cole (3.19)

DETF. Valdez (4.35)

FanDuel lines

MLNYY · DET

RL

Total

ParlayLab pick

HIGH

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Texas Rangers at Miami Marlins

6:40 PM ET

Rangers (37-40) visit the Marlins (40-38). Probable starters: T. Alexander (3.45) for Rangers, T. Phillips (3.59) for Marlins. Dome — no weather impact.

Pitchers

TEXT. Alexander (3.45)

MIAT. Phillips (3.59)

FanDuel lines

MLTEX · MIA

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Milwaukee Brewers at Cincinnati Reds

7:10 PM ET

Brewers (46-29) visit the Reds (37-39). Probable starters: B. Woodruff (2.59) for Brewers, B. Singer (4.72) for Reds. Weather at first pitch: 70°F, 9 mph wind.

Pitchers

MILB. Woodruff (2.59)

CINB. Singer (4.72)

FanDuel lines

MLMIL · CIN

RL

Total

ParlayLab pick

HIGH

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Cleveland Guardians at Chicago White Sox

7:40 PM ET

Guardians (41-37) visit the White Sox (39-37). Probable starters: G. Williams (3.72) for Guardians, A. Kay (3.96) for White Sox. Weather at first pitch: 63°F, 11 mph wind.

Pitchers

CLEG. Williams (3.72)

CWSA. Kay (3.96)

FanDuel lines

MLCLE · CWS

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

AZ at St. Louis Cardinals

7:45 PM ET

AZ (39-38) visit the Cardinals (41-34). Probable starters: M. Kelly (5.35) for AZ, A. Pallante (3.46) for Cardinals. Weather at first pitch: 70°F, 4 mph wind.

Pitchers

AZM. Kelly (5.35)

STLA. Pallante (3.46)

FanDuel lines

MLAZ · STL

RL

Total

ParlayLab pick

HIGH

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Boston Red Sox at Colorado Rockies

8:40 PM ET

Red Sox (31-44) visit the Rockies (30-48). Probable starters: J. Bennett (3.49) for Red Sox, R. Feltner (6.08) for Rockies. Weather at first pitch: 87°F, 10 mph wind.

Pitchers

BOSJ. Bennett (3.49)

COLR. Feltner (6.08)

FanDuel lines

MLBOS · COL

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Baltimore Orioles at Los Angeles Angels

9:38 PM ET

Orioles (37-42) visit the Angels (32-47). Probable starters: K. Bradish (3.70) for Orioles, S. Aldegheri (4.85) for Angels. Weather at first pitch: 72°F, 6 mph wind.

Pitchers

BALK. Bradish (3.70)

LAAS. Aldegheri (4.85)

FanDuel lines

MLBAL · LAA

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Atlanta Braves at San Diego Padres

10:10 PM ET

Braves (48-28) visit the Padres (39-37). Probable starters: G. Holmes (3.64) for Braves, M. King (3.38) for Padres. Weather at first pitch: 66°F, 6 mph wind.

Pitchers

ATLG. Holmes (3.64)

SDM. King (3.38)

FanDuel lines

MLATL · SD

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with Pro. You're charged when you subscribe — cancel anytime.