MLB PICKS

MLB Picks for June 21

ParlayLab's methodology engine grades the Sunday, June 21, 2026 MLB slate against the market. 15 games on the board — moneyline, run line, total, and player props. The full pick selections are available with a free 7-day Pro trial.

Cincinnati Reds at New York Yankees

1:35 PM ET

Reds (24-29) visit the Yankees (34-21). Probable starters: C. Burns (2.40) for Reds, E. Rodríguez (4.15) for Yankees. Weather at first pitch: 83°F, 7 mph wind.

Pitchers

CINC. Burns (2.40)

NYYE. Rodríguez (4.15)

FanDuel lines

MLCIN -104 · NYY -112

RL-1.5

TotalO/U 8.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Milwaukee Brewers at Atlanta Braves

1:35 PM ET

Brewers (34-21) visit the Braves (35-19). Probable starters: R. Gasser (4.15) for Brewers, B. Elder (4.01) for Braves. Weather at first pitch: 81°F, 3 mph wind.

Pitchers

MILR. Gasser (4.15)

ATLB. Elder (4.01)

FanDuel lines

MLMIL +100 · ATL -118

RL-1.5

TotalO/U 9

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Chicago White Sox at Detroit Tigers

1:40 PM ET

White Sox (31-24) visit the Tigers (22-34). Probable starters: D. Martin (3.08) for White Sox, K. Montero (3.68) for Tigers. Weather at first pitch: 77°F, 2 mph wind.

Pitchers

CWSD. Martin (3.08)

DETK. Montero (3.68)

FanDuel lines

MLCWS +102 · DET -120

RL-1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Toronto Blue Jays at Chicago Cubs

2:20 PM ET

Blue Jays (30-29) visit the Cubs (28-27). Probable starters: D. Cease (2.56) for Blue Jays, S. Imanaga (4.28) for Cubs. Weather at first pitch: 68°F, 7 mph wind.

Pitchers

TORD. Cease (2.56)

CHCS. Imanaga (4.28)

FanDuel lines

MLTOR -112 · CHC -104

RL-1.5

TotalO/U 7.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

San Diego Padres at Texas Rangers

2:35 PM ET

Padres (27-26) visit the Rangers (26-28). Probable starters: W. Peralta (2.23) for Padres, N. Eovaldi (4.02) for Rangers. Dome — no weather impact.

Pitchers

SDW. Peralta (2.23)

TEXN. Eovaldi (4.02)

FanDuel lines

MLSD +136 · TEX -162

RL+1.5

TotalO/U 8

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Pittsburgh Pirates at Colorado Rockies

3:10 PM ET

Pirates (27-29) visit the Rockies (23-33). Probable starters: J. Jones (4.37) for Pirates, M. Lorenzen (6.46) for Rockies. Weather at first pitch: 90°F, 18 mph wind.

Pitchers

PITJ. Jones (4.37)

COLM. Lorenzen (6.46)

FanDuel lines

MLPIT -144 · COL +122

RL-1.5

TotalO/U 11.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Minnesota Twins at AZ

3:15 PM ET

Twins (23-33) visit the AZ (26-26). Probable starters: M. Paredes (4.60) for Twins, J. Cabrera (4.73) for AZ. Weather at first pitch: 69°F, 13 mph wind.

Pitchers

MINM. Paredes (4.60)

AZJ. Cabrera (4.73)

FanDuel lines

MLMIN +114 · AZ -134

RL+1.5

TotalO/U 9.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Los Angeles Angels at Athletics

4:05 PM ET

Angels (19-34) visit the Athletics (27-27). Probable starters: R. Detmers (4.13) for Angels, J. Perkins (6.87) for Athletics. Weather at first pitch: 69°F, 16 mph wind.

Pitchers

LAAR. Detmers (4.13)

ATHJ. Perkins (6.87)

FanDuel lines

MLLAA +110 · ATH -130

RL+1.5

TotalO/U 9.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Boston Red Sox at Seattle Mariners

4:10 PM ET

Red Sox (24-31) visit the Mariners (28-28). Probable starters: P. Tolle (3.14) for Red Sox, L. Gilbert (3.19) for Mariners. Dome — no weather impact.

Pitchers

BOSP. Tolle (3.14)

SEAL. Gilbert (3.19)

FanDuel lines

MLBOS +108 · SEA -126

RL+1.5

TotalO/U 6.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

New York Mets at Philadelphia Phillies

7:20 PM ET

Mets (25-29) visit the Phillies (29-26). Probable starters: D. Peterson (6.75) for Mets, Z. Wheeler (2.28) for Phillies. Weather at first pitch: 82°F, 8 mph wind.

Pitchers

NYMD. Peterson (6.75)

PHIZ. Wheeler (2.28)

FanDuel lines

MLNYM +158 · PHI -188

RL+1.5

TotalO/U 8.5

ParlayLab pick

HIGH

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with a Pro trial. No card charged for the first 7 days.