MLB PICKS

MLB Picks for June 21

ParlayLab's methodology engine grades the Sunday, June 21, 2026 MLB slate against the market. 14 games with 2 HIGH-confidence picks — moneyline, run line, total, and player props. The full pick selections are available with Pro.

Cincinnati Reds at New York Yankees

1:35 PM ET

Reds (36-39) visit the Yankees (46-29). Probable starters: C. Burns (2.77) for Reds, E. Rodríguez (4.76) for Yankees. Weather at first pitch: 83°F, 7 mph wind.

Pitchers

CINC. Burns (2.77)

NYYE. Rodríguez (4.76)

FanDuel lines

MLCIN · NYY

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Milwaukee Brewers at Atlanta Braves

1:35 PM ET

Brewers (45-29) visit the Braves (48-27). Probable starters: R. Gasser (4.59) for Brewers, B. Elder (3.92) for Braves. Weather at first pitch: 81°F, 3 mph wind.

Pitchers

MILR. Gasser (4.59)

ATLB. Elder (3.92)

FanDuel lines

MLMIL · ATL

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Chicago White Sox at Detroit Tigers

1:40 PM ET

White Sox (39-36) visit the Tigers (32-44). Probable starters: D. Martin (4.17) for White Sox, K. Montero (3.30) for Tigers. Weather at first pitch: 77°F, 2 mph wind.

Pitchers

CWSD. Martin (4.17)

DETK. Montero (3.30)

FanDuel lines

MLCWS · DET

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

San Diego Padres at Texas Rangers

2:35 PM ET

Padres (39-36) visit the Rangers (36-40). Probable starters: W. Peralta (3.46) for Padres, N. Eovaldi (4.31) for Rangers. Dome — no weather impact.

Pitchers

SDW. Peralta (3.46)

TEXN. Eovaldi (4.31)

FanDuel lines

MLSD · TEX

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Pittsburgh Pirates at Colorado Rockies

3:10 PM ET

Pirates (38-39) visit the Rockies (30-47). Probable starters: J. Jones (4.83) for Pirates, M. Lorenzen (6.83) for Rockies. Weather at first pitch: 90°F, 18 mph wind.

Pitchers

PITJ. Jones (4.83)

COLM. Lorenzen (6.83)

FanDuel lines

MLPIT · COL

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Minnesota Twins at AZ

3:15 PM ET

Twins (37-41) visit the AZ (39-37). Probable starters: M. Paredes (4.72) for Twins, J. Cabrera (5.60) for AZ. Weather at first pitch: 69°F, 13 mph wind.

Pitchers

MINM. Paredes (4.72)

AZJ. Cabrera (5.60)

FanDuel lines

MLMIN · AZ

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Los Angeles Angels at Athletics

4:05 PM ET

Angels (31-47) visit the Athletics (38-39). Probable starters: R. Detmers (3.62) for Angels, J. Perkins (6.68) for Athletics. Weather at first pitch: 69°F, 16 mph wind.

Pitchers

LAAR. Detmers (3.62)

ATHJ. Perkins (6.68)

FanDuel lines

MLLAA · ATH

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Boston Red Sox at Seattle Mariners

4:10 PM ET

Red Sox (31-43) visit the Mariners (39-39). Probable starters: P. Tolle (3.08) for Red Sox, L. Gilbert (3.36) for Mariners. Dome — no weather impact.

Pitchers

BOSP. Tolle (3.08)

SEAL. Gilbert (3.36)

FanDuel lines

MLBOS · SEA

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

New York Mets at Philadelphia Phillies

7:20 PM ET

Mets (34-42) visit the Phillies (41-35). Probable starters: D. Peterson (5.17) for Mets, Z. Wheeler (3.40) for Phillies. Weather at first pitch: 82°F, 8 mph wind.

Pitchers

NYMD. Peterson (5.17)

PHIZ. Wheeler (3.40)

FanDuel lines

MLNYM · PHI

RL

Total

ParlayLab pick

HIGH

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with Pro. You're charged when you subscribe — cancel anytime.