MLB PICKS

MLB Picks for May 23

ParlayLab's methodology engine grades the Saturday, May 23, 2026 MLB slate against the market. 15 games with 4 HIGH-confidence picks — moneyline, run line, total, and player props. The full pick selections are available with Pro.

Tampa Bay Rays at New York Yankees

1:35 PM ET

Rays (34-15) visit the Yankees (30-22). Probable starters: D. Rasmussen (2.95) for Rays, R. Weathers (3.56) for Yankees. Weather at first pitch: 72°F.

Pitchers

TBD. Rasmussen (2.95)

NYYR. Weathers (3.56)

FanDuel lines

MLTB · NYY

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Houston Astros at Chicago Cubs

2:20 PM ET

Astros (21-31) visit the Cubs (29-22). Probable starters: K. Teng (4.03) for Astros, C. Rea (4.67) for Cubs. Weather at first pitch: 63°F, 5 mph wind.

Pitchers

HOUK. Teng (4.03)

CHCC. Rea (4.67)

FanDuel lines

MLHOU · CHC

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Minnesota Twins at Boston Red Sox

4:10 PM ET

Twins (24-27) visit the Red Sox (22-28). Probable starters: T. Bradley (3.97) for Twins, J. Morán (2.81) for Red Sox. Weather at first pitch: 60°F, 9 mph wind.

Pitchers

MINT. Bradley (3.97)

BOSJ. Morán (2.81)

FanDuel lines

MLMIN · BOS

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

New York Mets at Miami Marlins

4:10 PM ET

Mets (22-29) visit the Marlins (23-29). Probable starters: F. Peralta (5.33) for Mets, M. Meyer (2.58) for Marlins. Dome — no weather impact.

Pitchers

NYMF. Peralta (5.33)

MIAM. Meyer (2.58)

FanDuel lines

MLNYM · MIA

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Athletics at San Diego Padres

9:40 PM ET

Athletics (26-25) visit the Padres (30-20). Probable starters: J. Ginn (3.60) for Athletics, L. Giolito (5.16) for Padres. Weather at first pitch: 72°F.

Pitchers

ATHJ. Ginn (3.60)

SDL. Giolito (5.16)

FanDuel lines

MLATH · SD

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Texas Rangers at Los Angeles Angels

10:05 PM ET

Rangers (24-26) visit the Angels (18-34). Probable starters: N. Eovaldi (4.31) for Rangers, W. Ureña (2.94) for Angels. Weather at first pitch: 72°F.

Pitchers

TEXN. Eovaldi (4.31)

LAAW. Ureña (2.94)

FanDuel lines

MLTEX · LAA

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Colorado Rockies at AZ

10:10 PM ET

Rockies (20-32) visit the AZ (26-24). Probable starters: M. Lorenzen (6.83) for Rockies, Z. Gallen (6.36) for AZ. Weather at first pitch: 72°F.

Pitchers

COLM. Lorenzen (6.83)

AZZ. Gallen (6.36)

FanDuel lines

MLCOL · AZ

RL

Total

ParlayLab pick

HIGH

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with Pro. You're charged when you subscribe — cancel anytime.