MLB PICKS

MLB Picks for May 23

ParlayLab's methodology engine grades the Saturday, May 23, 2026 MLB slate against the market. 15 games with 3 HIGH-confidence picks — moneyline, run line, total, and player props. The full pick selections are available with a free 7-day Pro trial.

St. Louis Cardinals at Cincinnati Reds

1:10 PM ET

Cardinals (18-13) visit the Reds (16-15). Probable starters: A. Pallante (3.76) for Cardinals, C. Paddack (6.86) for Reds. Weather at first pitch: 72°F.

Pitchers

STLA. Pallante (3.76)

CINC. Paddack (6.86)

FanDuel lines

MLSTL -104 · CIN -112

RL-1.5

TotalO/U 9.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

Unlock with Pro

3 qualifying picks across moneyline, run line, and totals.

Tampa Bay Rays at New York Yankees

1:35 PM ET

Rays (24-8) visit the Yankees (19-14). Probable starters: D. Rasmussen (2.78) for Rays, R. Weathers (3.14) for Yankees. Weather at first pitch: 72°F.

Pitchers

TBD. Rasmussen (2.78)

NYYR. Weathers (3.14)

FanDuel lines

MLTB +120 · NYY -142

RL+1.5

TotalO/U 7

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

Unlock with Pro

3 qualifying picks across moneyline, run line, and totals.

Houston Astros at Chicago Cubs

2:20 PM ET

Astros (12-19) visit the Cubs (20-12). Probable starters: K. Teng (2.19) for Astros, C. Rea (4.83) for Cubs. Weather at first pitch: 63°F.

Pitchers

HOUK. Teng (2.19)

CHCC. Rea (4.83)

FanDuel lines

MLHOU +126 · CHC -148

RL+1.5

TotalO/U 7

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

Unlock with Pro

3 qualifying picks across moneyline, run line, and totals.

Minnesota Twins at Boston Red Sox

4:10 PM ET

Twins (12-20) visit the Red Sox (16-16). Probable starters: T. Bradley (2.77) for Twins, J. Morán (2.81) for Red Sox. Weather at first pitch: 60°F.

Pitchers

MINT. Bradley (2.77)

BOSJ. Morán (2.81)

FanDuel lines

MLMIN +106 · BOS -124

RL+1.5

TotalO/U 7.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

Unlock with Pro

3 qualifying picks across moneyline, run line, and totals.

New York Mets at Miami Marlins

4:10 PM ET

Mets (14-17) visit the Marlins (14-18). Probable starters: F. Peralta (3.52) for Mets, M. Meyer (2.52) for Marlins. Dome — no weather impact.

Pitchers

NYMF. Peralta (3.52)

MIAM. Meyer (2.52)

FanDuel lines

MLNYM -104 · MIA -112

RL-1.5

TotalO/U 7.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

Unlock with Pro

3 qualifying picks across moneyline, run line, and totals.

Athletics at San Diego Padres

9:40 PM ET

Athletics (17-16) visit the Padres (18-13). Probable starters: J. Ginn (3.19) for Athletics, L. Giolito (2.70) for Padres. Weather at first pitch: 72°F.

Pitchers

ATHJ. Ginn (3.19)

SDL. Giolito (2.70)

FanDuel lines

MLATH -126 · SD +108

RL-1.5

TotalO/U 8

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

Unlock with Pro

3 qualifying picks across moneyline, run line, and totals.

Texas Rangers at Los Angeles Angels

10:05 PM ET

Rangers (14-17) visit the Angels (8-24). Probable starters: N. Eovaldi (3.65) for Rangers, W. Ureña (2.58) for Angels. Weather at first pitch: 72°F.

Pitchers

TEXN. Eovaldi (3.65)

LAAW. Ureña (2.58)

FanDuel lines

MLTEX -138 · LAA +118

RL-1.5

TotalO/U 7.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

Unlock with Pro

3 qualifying picks across moneyline, run line, and totals.

Colorado Rockies at AZ

10:10 PM ET

Rockies (13-20) visit the AZ (15-15). Probable starters: M. Lorenzen (7.21) for Rockies, Z. Gallen (4.80) for AZ. Weather at first pitch: 72°F.

Pitchers

COLM. Lorenzen (7.21)

AZZ. Gallen (4.80)

FanDuel lines

MLCOL +158 · AZ -188

RL+1.5

TotalO/U 9.5

ParlayLab pick

HIGH

MED edge

ML / RL / O-U projection

Unlock with Pro

3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with a Pro trial. No card charged for the first 7 days.