MLB PICKS

MLB Picks for September 5

ParlayLab's methodology engine grades the Saturday, September 5, 2026 MLB slate against the market. 15 games on the board — moneyline, run line, total, and player props. The full pick selections are available with Pro.

San Francisco Giants at New York Mets

4:10 PM ET

Giants (58-83) visit the Mets (64-77). Probable starters: A. Molina (2.79) for Giants, Z. Thornton (2.93) for Mets. Weather at first pitch: 79°F, 10 mph wind.

Pitchers

SFA. Molina (2.79)

NYMZ. Thornton (2.93)

FanDuel lines

MLSF +142 · NYM -168

RL+1.5

TotalO/U 8

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Chicago Cubs at Miami Marlins

4:10 PM ET

Cubs (80-61) visit the Marlins (71-71). Probable starters: J. Assad (3.46) for Cubs, R. Gusto (3.86) for Marlins. Dome — no weather impact.

Pitchers

CHCJ. Assad (3.46)

MIAR. Gusto (3.86)

FanDuel lines

MLCHC -126 · MIA +108

RL-1.5

TotalO/U 8

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Atlanta Braves at Philadelphia Phillies

6:05 PM ET

Braves (84-57) visit the Phillies (78-62). Probable starters: M. Pérez (3.05) for Braves, Z. Wheeler (3.31) for Phillies. Weather at first pitch: 80°F, 7 mph wind.

Pitchers

ATLM. Pérez (3.05)

PHIZ. Wheeler (3.31)

FanDuel lines

MLATL +142 · PHI -168

RL+1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Detroit Tigers at Cleveland Guardians

6:10 PM ET

Tigers (64-77) visit the Guardians (71-70). Probable starters: F. Valdez (4.36) for Tigers, P. Messick (2.46) for Guardians. Weather at first pitch: 75°F, 10 mph wind.

Pitchers

DETF. Valdez (4.36)

CLEP. Messick (2.46)

FanDuel lines

MLDET +134 · CLE -158

RL+1.5

TotalO/U 7

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Los Angeles Angels at Pittsburgh Pirates

6:40 PM ET

Angels (52-85) visit the Pirates (69-71). Probable starters: Y. Kikuchi (5.65) for Angels, B. Ashcraft (3.59) for Pirates. Weather at first pitch: 76°F, 4 mph wind.

Pitchers

LAAY. Kikuchi (5.65)

PITB. Ashcraft (3.59)

FanDuel lines

MLLAA +154 · PIT -184

RL+1.5

TotalO/U 7.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Milwaukee Brewers at Cincinnati Reds

6:40 PM ET

Brewers (87-54) visit the Reds (67-74). Probable starters: D. May (4.69) for Brewers, A. Abbott (4.49) for Reds. Weather at first pitch: 89°F, 6 mph wind.

Pitchers

MILD. May (4.69)

CINA. Abbott (4.49)

FanDuel lines

MLMIL -156 · CIN +132

RL-1.5

TotalO/U 9.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Boston Red Sox at Baltimore Orioles

7:05 PM ET

Red Sox (76-65) visit the Orioles (68-73). Probable starters: S. Gray (2.82) for Red Sox, C. Bassitt (4.97) for Orioles. Weather at first pitch: 80°F, 3 mph wind.

Pitchers

BOSS. Gray (2.82)

BALC. Bassitt (4.97)

FanDuel lines

MLBOS -130 · BAL +110

RL-1.5

TotalO/U 7.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Tampa Bay Rays at Texas Rangers

7:05 PM ET

Rays (84-57) visit the Rangers (69-71). Probable starters: D. Rasmussen (2.95) for Rays, J. deGrom (4.00) for Rangers. Dome — no weather impact.

Pitchers

TBD. Rasmussen (2.95)

TEXJ. deGrom (4.00)

FanDuel lines

MLTB -108 · TEX -108

RL-1.5

TotalO/U 6.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Toronto Blue Jays at Kansas City Royals

7:10 PM ET

Blue Jays (71-71) visit the Royals (63-78). Probable starters: M. Scherzer (6.16) for Blue Jays, S. Lugo (5.03) for Royals. Weather at first pitch: 100°F, 6 mph wind.

Pitchers

TORM. Scherzer (6.16)

KCS. Lugo (5.03)

FanDuel lines

MLTOR -106 · KC -110

RL-1.5

TotalO/U 9.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Minnesota Twins at Chicago White Sox

7:10 PM ET

Twins (67-74) visit the White Sox (74-67). Probable starters: T. Bradley (3.85) for Twins, A. Kay (4.28) for White Sox. Weather at first pitch: 74°F, 13 mph wind.

Pitchers

MINT. Bradley (3.85)

CWSA. Kay (4.28)

FanDuel lines

MLMIN +106 · CWS -124

RL+1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

AZ at Houston Astros

7:15 PM ET

AZ (73-68) visit the Astros (73-69). Probable starters: B. Pfaadt (3.49) for AZ, E. Pecko (6.23) for Astros. Dome — no weather impact.

Pitchers

AZB. Pfaadt (3.49)

HOUE. Pecko (6.23)

FanDuel lines

MLAZ -108 · HOU -108

RL-1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

New York Yankees at San Diego Padres

7:15 PM ET

Yankees (80-61) visit the Padres (73-66). Probable starters: C. Rodón (3.20) for Yankees, R. Ray (3.14) for Padres. Weather at first pitch: 84°F, 9 mph wind.

Pitchers

NYYC. Rodón (3.20)

SDR. Ray (3.14)

FanDuel lines

MLNYY +110 · SD -130

RL+1.5

TotalO/U 7.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

St. Louis Cardinals at Colorado Rockies

8:10 PM ET

Cardinals (69-70) visit the Rockies (54-85). Probable starters: M. Liberatore (5.41) for Cardinals, M. Adams (3.00) for Rockies. Weather at first pitch: 92°F, 4 mph wind.

Pitchers

STLM. Liberatore (5.41)

COLM. Adams (3.00)

FanDuel lines

MLSTL -120 · COL +102

RL-1.5

TotalO/U 10.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Athletics at Seattle Mariners

9:40 PM ET

Athletics (54-86) visit the Mariners (65-73). Probable starters: J. Springs (6.37) for Athletics, G. Kirby (4.19) for Mariners. Dome — no weather impact.

Pitchers

ATHJ. Springs (6.37)

SEAG. Kirby (4.19)

FanDuel lines

MLATH +200 · SEA -245

RL+1.5

TotalO/U 7.5

ParlayLab pick

HIGH

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with Pro. You're charged when you subscribe — cancel anytime.