MLB PICKS

MLB Picks for September 1

ParlayLab's methodology engine grades the Tuesday, September 1, 2026 MLB slate against the market. 15 games with 1 HIGH-confidence pick — moneyline, run line, total, and player props. The full pick selections are available with Pro.

San Diego Padres at Cincinnati Reds

6:40 PM ET

Padres (72-64) visit the Reds (65-73). Probable starters: R. Vásquez (4.02) for Padres, N. Lodolo (5.24) for Reds. Weather at first pitch: 93°F, 5 mph wind.

Pitchers

SDR. Vásquez (4.02)

CINN. Lodolo (5.24)

FanDuel lines

MLSD -136 · CIN +116

RL-1.5

TotalO/U 9

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

New York Mets at Tampa Bay Rays

6:40 PM ET

Mets (62-76) visit the Rays (82-55). Probable starters: S. Manaea (4.70) for Mets, F. Peralta (5.11) for Rays. Dome — no weather impact.

Pitchers

NYMS. Manaea (4.70)

TBF. Peralta (5.11)

FanDuel lines

MLNYM +116 · TB -136

RL+1.5

TotalO/U 7.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Toronto Blue Jays at Cleveland Guardians

6:40 PM ET

Blue Jays (68-70) visit the Guardians (68-68). Probable starters: S. Miles (2.84) for Blue Jays, G. Williams (3.98) for Guardians. Weather at first pitch: 88°F, 10 mph wind.

Pitchers

TORS. Miles (2.84)

CLEG. Williams (3.98)

FanDuel lines

MLTOR +154 · CLE -184

RL+1.5

TotalO/U 7.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Seattle Mariners at Boston Red Sox

6:45 PM ET

Mariners (63-73) visit the Red Sox (74-63). Probable starters: B. Woo (4.36) for Mariners, J. Paez (18.00) for Red Sox. Weather at first pitch: 65°F, 1 mph wind.

Pitchers

SEAB. Woo (4.36)

BOSJ. Paez (18.00)

FanDuel lines

MLSEA +100 · BOS -118

RL-1.5

TotalO/U 7.5

ParlayLab pick

LOW

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Atlanta Braves at Washington Nationals

6:45 PM ET

Braves (82-56) visit the Nationals (66-74). Probable starters: A. Smith-Shawver (7.13) for Braves, J. Irvin (5.62) for Nationals. Weather at first pitch: 93°F, 3 mph wind.

Pitchers

ATLA. Smith-Shawver (7.13)

WSHJ. Irvin (5.62)

FanDuel lines

MLATL -148 · WSH +126

RL-1.5

TotalO/U 9.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Detroit Tigers at Minnesota Twins

7:40 PM ET

Tigers (63-74) visit the Twins (66-72). Probable starters: T. Melton (2.20) for Tigers, A. Morris (3.90) for Twins. Weather at first pitch: 85°F, 6 mph wind.

Pitchers

DETT. Melton (2.20)

MINA. Morris (3.90)

FanDuel lines

MLDET -104 · MIN -112

RL-1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Miami Marlins at Kansas City Royals

7:40 PM ET

Marlins (69-69) visit the Royals (62-75). Probable starters: T. Phillips (3.43) for Marlins, R. Dobnak (2.65) for Royals. Weather at first pitch: 96°F, 8 mph wind.

Pitchers

MIAT. Phillips (3.43)

KCR. Dobnak (2.65)

FanDuel lines

MLMIA -104 · KC -112

RL-1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Milwaukee Brewers at Chicago Cubs

7:40 PM ET

Brewers (84-53) visit the Cubs (78-59). Probable starters: R. Gasser (4.57) for Brewers, M. Boyd (3.99) for Cubs. Weather at first pitch: 78°F, 5 mph wind.

Pitchers

MILR. Gasser (4.57)

CHCM. Boyd (3.99)

FanDuel lines

MLMIL -162 · CHC +136

RL-1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Athletics at Texas Rangers

8:05 PM ET

Athletics (53-85) visit the Rangers (67-69). Probable starters: B. Basso (4.32) for Athletics, M. Gore (4.40) for Rangers. Dome — no weather impact.

Pitchers

ATHB. Basso (4.32)

TEXM. Gore (4.40)

FanDuel lines

MLATH +176 · TEX -210

RL+1.5

TotalO/U 7.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Chicago White Sox at Houston Astros

8:10 PM ET

White Sox (72-65) visit the Astros (70-68). Probable starters: S. Burke (3.32) for White Sox, R. Blanco (6.59) for Astros. Dome — no weather impact.

Pitchers

CWSS. Burke (3.32)

HOUR. Blanco (6.59)

FanDuel lines

MLCWS -112 · HOU -104

RL-1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Baltimore Orioles at Colorado Rockies

8:40 PM ET

Orioles (68-69) visit the Rockies (52-84). Probable starters: K. Bradish (4.03) for Orioles, G. Hughes (6.19) for Rockies. Weather at first pitch: 82°F, 7 mph wind.

Pitchers

BALK. Bradish (4.03)

COLG. Hughes (6.19)

FanDuel lines

MLBAL -162 · COL +136

RL-1.5

TotalO/U 11

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

New York Yankees at Los Angeles Angels

9:38 PM ET

Yankees (78-60) visit the Angels (52-82). Probable starters: G. Cole (3.29) for Yankees, G. Rodriguez (6.03) for Angels. Weather at first pitch: 74°F, 6 mph wind.

Pitchers

NYYG. Cole (3.29)

LAAG. Rodriguez (6.03)

FanDuel lines

MLNYY -194 · LAA +162

RL-1.5

TotalO/U 7.5

ParlayLab pick

HIGH

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Philadelphia Phillies at AZ

9:40 PM ET

Phillies (77-60) visit the AZ (72-66). Probable starters: J. Luzardo (3.09) for Phillies, E. Rodriguez (2.50) for AZ. Weather at first pitch: 76°F, 11 mph wind.

Pitchers

PHIJ. Luzardo (3.09)

AZE. Rodriguez (2.50)

FanDuel lines

MLPHI -134 · AZ +114

RL-1.5

TotalO/U 7.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with Pro. You're charged when you subscribe — cancel anytime.