MLB PICKS

MLB Picks for May 31

ParlayLab's methodology engine grades the Sunday, May 31, 2026 MLB slate against the market. 15 games with 4 HIGH-confidence picks — moneyline, run line, total, and player props. The full pick selections are available with a free 7-day Pro trial.

San Diego Padres at Washington Nationals

1:35 PM ET

Padres (20-17) visit the Nationals (21-19). Probable starters: G. Canning (6.71) for Padres, Z. Littell (5.29) for Nationals. Weather at first pitch: 77°F, 2 mph wind.

Pitchers

SDG. Canning (6.71)

WSHZ. Littell (5.29)

FanDuel lines

MLSD -116 · WSH -102

RL-1.5

TotalO/U 9.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Minnesota Twins at Pittsburgh Pirates

1:35 PM ET

Twins (15-24) visit the Pirates (20-19). Probable starters: Z. Matthews (4.57) for Twins, B. Ashcraft (3.49) for Pirates. Weather at first pitch: 75°F, 3 mph wind.

Pitchers

MINZ. Matthews (4.57)

PITB. Ashcraft (3.49)

FanDuel lines

MLMIN +140 · PIT -166

RL+1.5

TotalO/U 7.5

ParlayLab pick

LOW

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Boston Red Sox at Cleveland Guardians

1:40 PM ET

Red Sox (17-21) visit the Guardians (22-17). Probable starters: R. Suarez (2.94) for Red Sox, T. Bibee (4.06) for Guardians. Weather at first pitch: 73°F, 5 mph wind.

Pitchers

BOSR. Suarez (2.94)

CLET. Bibee (4.06)

FanDuel lines

MLBOS -102 · CLE -116

RL-1.5

TotalO/U 7

ParlayLab pick

HIGH

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Los Angeles Angels at Tampa Bay Rays

1:40 PM ET

Angels (12-25) visit the Rays (25-12). Probable starters: J. Kochanowicz (5.23) for Angels, S. McClanahan (3.05) for Rays. Dome — no weather impact.

Pitchers

LAAJ. Kochanowicz (5.23)

TBS. McClanahan (3.05)

FanDuel lines

MLLAA +176 · TB -210

RL+1.5

TotalO/U 8

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Atlanta Braves at Cincinnati Reds

1:40 PM ET

Braves (27-11) visit the Reds (19-18). Probable starters: S. Strider (4.00) for Braves, N. Lodolo (4.68) for Reds. Weather at first pitch: 78°F, 5 mph wind.

Pitchers

ATLS. Strider (4.00)

CINN. Lodolo (4.68)

FanDuel lines

MLATL -124 · CIN +106

RL-1.5

TotalO/U 8.5

ParlayLab pick

HIGH

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Miami Marlins at New York Mets

1:40 PM ET

Marlins (17-21) visit the Mets (16-21). Probable starters: J. King (2.48) for Marlins, N. McLean (3.73) for Mets. Weather at first pitch: 76°F, 11 mph wind.

Pitchers

MIAJ. King (2.48)

NYMN. McLean (3.73)

FanDuel lines

MLMIA +136 · NYM -162

RL+1.5

TotalO/U 7.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Detroit Tigers at Chicago White Sox

2:10 PM ET

Tigers (13-27) visit the White Sox (23-15). Probable starters: K. Montero (3.68) for Tigers, S. Burke (3.56) for White Sox. Weather at first pitch: 72°F.

Pitchers

DETK. Montero (3.68)

CWSS. Burke (3.56)

FanDuel lines

MLDET +114 · CWS -134

RL+1.5

TotalO/U 8

ParlayLab pick

HIGH

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Milwaukee Brewers at Houston Astros

2:10 PM ET

Brewers (24-13) visit the Astros (17-21). Probable starters: J. Misiorowski (1.47) for Brewers, T. Imai (6.06) for Astros. Dome — no weather impact.

Pitchers

MILJ. Misiorowski (1.47)

HOUT. Imai (6.06)

FanDuel lines

MLMIL -200 · HOU +168

RL-1.5

TotalO/U 7.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

New York Yankees at Athletics

4:05 PM ET

Yankees (23-15) visit the Athletics (19-20). Probable starters: W. Warren (4.15) for Yankees, J. Lopez (7.04) for Athletics. Weather at first pitch: 72°F.

Pitchers

NYYW. Warren (4.15)

ATHJ. Lopez (7.04)

FanDuel lines

MLNYY -176 · ATH +148

RL-1.5

TotalO/U 9.5

ParlayLab pick

HIGH

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

AZ at Seattle Mariners

4:10 PM ET

AZ (19-16) visit the Mariners (19-18). Probable starters: M. Kelly (5.71) for AZ, B. Miller (2.18) for Mariners. Dome — no weather impact.

Pitchers

AZM. Kelly (5.71)

SEAB. Miller (2.18)

FanDuel lines

MLAZ +120 · SEA -142

RL+1.5

TotalO/U 7.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Chicago Cubs at St. Louis Cardinals

7:20 PM ET

Cubs (22-17) visit the Cardinals (20-17). Probable starters: J. Wicks (10.45) for Cubs, M. Liberatore (5.34) for Cardinals. Weather at first pitch: 78°F, 4 mph wind.

Pitchers

CHCJ. Wicks (10.45)

STLM. Liberatore (5.34)

FanDuel lines

MLCHC +100 · STL -118

RL-1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with a Pro trial. No card charged for the first 7 days.