MLB PICKS

MLB Picks for May 29

ParlayLab's methodology engine grades the Friday, May 29, 2026 MLB slate against the market. 15 games with 1 HIGH-confidence pick — moneyline, run line, total, and player props. The full pick selections are available with a free 7-day Pro trial.

Atlanta Braves at Cincinnati Reds

6:40 PM ET

Braves (25-11) visit the Reds (19-16). Probable starters: G. Holmes (3.78) for Braves, C. Paddack (6.86) for Reds. Weather at first pitch: 72°F.

Pitchers

ATLG. Holmes (3.78)

CINC. Paddack (6.86)

FanDuel lines

MLATL -136 · CIN +116

RL-1.5

TotalO/U 9.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Boston Red Sox at Cleveland Guardians

7:10 PM ET

Red Sox (16-20) visit the Guardians (21-16). Probable starters: T. Samaniego (2.95) for Red Sox, S. Cecconi (5.18) for Guardians. Weather at first pitch: 72°F.

Pitchers

BOST. Samaniego (2.95)

CLES. Cecconi (5.18)

FanDuel lines

MLBOS +108 · CLE -126

RL+1.5

TotalO/U 8

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Miami Marlins at New York Mets

7:10 PM ET

Marlins (17-19) visit the Mets (14-21). Probable starters: M. Meyer (2.52) for Marlins, F. Peralta (3.52) for Mets. Weather at first pitch: 76°F.

Pitchers

MIAM. Meyer (2.52)

NYMF. Peralta (3.52)

FanDuel lines

MLMIA -104 · NYM -112

RL-1.5

TotalO/U 7.5

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Chicago Cubs at St. Louis Cardinals

7:15 PM ET

Cubs (21-16) visit the Cardinals (19-16). Probable starters: S. Imanaga (4.04) for Cubs, A. Pallante (3.76) for Cardinals. Weather at first pitch: 76°F.

Pitchers

CHCS. Imanaga (4.04)

STLA. Pallante (3.76)

FanDuel lines

MLCHC -132 · STL +112

RL-1.5

TotalO/U 7.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Detroit Tigers at Chicago White Sox

7:40 PM ET

Tigers (13-25) visit the White Sox (21-15). Probable starters: T. Melton (1.42) for Tigers, E. Fedde (5.47) for White Sox. Weather at first pitch: 72°F.

Pitchers

DETT. Melton (1.42)

CWSE. Fedde (5.47)

FanDuel lines

MLDET -108 · CWS -108

RL-1.5

TotalO/U 8.5

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

New York Yankees at Athletics

9:40 PM ET

Yankees (22-14) visit the Athletics (18-19). Probable starters: C. Rodón (4.15) for Yankees, L. Severino (4.23) for Athletics. Weather at first pitch: 62°F.

Pitchers

NYYC. Rodón (4.15)

ATHL. Severino (4.23)

FanDuel lines

MLNYY -142 · ATH +120

RL-1.5

TotalO/U 9.5

ParlayLab pick

HIGH

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

AZ at Seattle Mariners

10:10 PM ET

AZ (19-15) visit the Mariners (18-18). Probable starters: Z. Gallen (4.80) for AZ, G. Kirby (3.54) for Mariners. Dome — no weather impact.

Pitchers

AZZ. Gallen (4.80)

SEAG. Kirby (3.54)

FanDuel lines

MLAZ +120 · SEA -142

RL+1.5

TotalO/U 7

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

Unlock with Pro

3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with a Pro trial. No card charged for the first 7 days.