MLB PICKS

MLB Picks for May 20

ParlayLab's methodology engine grades the Wednesday, May 20, 2026 MLB slate against the market. 15 games with 4 HIGH-confidence picks — moneyline, run line, total, and player props. The full pick selections are available with a free 7-day Pro trial.

Houston Astros at Minnesota Twins

1:40 PM ET

Astros (11-18) visit the Twins (10-20). Probable starters: M. Burrows (5.58) for Astros, J. Ryan (3.61) for Twins. Weather at first pitch: 72°F.

Pitchers

HOUM. Burrows (5.58)

MINJ. Ryan (3.61)

FanDuel lines

MLHOU · MIN

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Texas Rangers at Colorado Rockies

3:10 PM ET

Rangers (13-16) visit the Rockies (12-18). Probable starters: J. Leiter (4.86) for Rangers, K. Freeland (7.25) for Rockies. Weather at first pitch: 72°F.

Pitchers

TEXJ. Leiter (4.86)

COLK. Freeland (7.25)

FanDuel lines

MLTEX · COL

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

San Francisco Giants at AZ

3:40 PM ET

Giants (13-16) visit the AZ (13-14). Probable starters: T. Mahle (5.67) for Giants, M. Kelly (5.71) for AZ. Weather at first pitch: 72°F.

Pitchers

SFT. Mahle (5.67)

AZM. Kelly (5.71)

FanDuel lines

MLSF · AZ

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Atlanta Braves at Miami Marlins

6:40 PM ET

Braves (20-9) visit the Marlins (13-16). Probable starters: C. Sale (2.27) for Braves, J. Junk (4.80) for Marlins. Dome — no weather impact.

Pitchers

ATLC. Sale (2.27)

MIAJ. Junk (4.80)

FanDuel lines

MLATL · MIA

RL

Total

ParlayLab pick

HIGH

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

New York Mets at Washington Nationals

6:45 PM ET

Mets (13-15) visit the Nationals (15-16). Probable starters: Z. Thornton (4.35) for Mets, Z. Littell (5.29) for Nationals. Weather at first pitch: 75°F, 7 mph wind.

Pitchers

NYMZ. Thornton (4.35)

WSHZ. Littell (5.29)

FanDuel lines

MLNYM · WSH

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Toronto Blue Jays at New York Yankees

7:05 PM ET

Blue Jays (14-17) visit the Yankees (19-11). Probable starters: T. Yesavage (3.34) for Blue Jays, C. Schlittler (2.08) for Yankees. Weather at first pitch: 72°F.

Pitchers

TORT. Yesavage (3.34)

NYYC. Schlittler (2.08)

FanDuel lines

MLTOR · NYY

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Milwaukee Brewers at Chicago Cubs

7:40 PM ET

Brewers (19-10) visit the Cubs (20-10). Probable starters: K. Harrison (2.82) for Brewers, E. Cabrera (5.21) for Cubs. Weather at first pitch: 52°F, 13 mph wind.

Pitchers

MILK. Harrison (2.82)

CHCE. Cabrera (5.21)

FanDuel lines

MLMIL · CHC

RL

Total

ParlayLab pick

MED

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Pittsburgh Pirates at St. Louis Cardinals

7:45 PM ET

Pirates (13-16) visit the Cardinals (18-11). Probable starters: C. Mlodzinski (3.76) for Pirates, M. McGreevy (3.12) for Cardinals. Weather at first pitch: 64°F, 4 mph wind.

Pitchers

PITC. Mlodzinski (3.76)

STLM. McGreevy (3.12)

FanDuel lines

MLPIT · STL

RL

Total

ParlayLab pick

LOW

MED edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

Athletics at Los Angeles Angels

9:38 PM ET

Athletics (15-15) visit the Angels (7-22). Probable starters: A. Civale (4.92) for Athletics, J. Kochanowicz (5.23) for Angels. Weather at first pitch: 72°F.

Pitchers

ATHA. Civale (4.92)

LAAJ. Kochanowicz (5.23)

FanDuel lines

MLATH · LAA

RL

Total

ParlayLab pick

HIGH

HIGH edge

ML / RL / O-U projection

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3 qualifying picks across moneyline, run line, and totals.

How ParlayLab grades the slate

Our methodology engine projects each MLB game using a market-blended model that combines team-level offense, starting-pitcher form, ballpark factors, weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. The engine outputs a moneyline, run-line, and total projection for every matchup and grades each pick HIGH / MED / LOW confidence based on the edge versus the FanDuel line.

Player props go through a separate Poisson projection layer per stat — hits, home runs, total bases, RBIs, runs scored, hits+runs+RBIs, and pitcher strikeouts. Each prop projection accounts for the batter-vs-pitcher history, recent rolling form, opposing pitcher ERA / WHIP / K%, ballpark-by-handedness factors, and weather. Props with strong projection-vs-line edges show up bright green; weak ones drop to orange or red.

Free users see the top picks for each market per slate plus the per-game matchup context shown above. The full pick selections, every prop on the board, the prop filter builder, and the full Game Detail + Player Detail breakdowns unlock with a Pro trial. No card charged for the first 7 days.