MLB PICKS / FRIDAY, SEPTEMBER 25, 2026

Los Angeles Angels at Seattle Mariners

Los Angeles Angels (59-95) visit the Seattle Mariners (72-82) at 10:10 PM ET. Probable starters: R. Detmers (3.36) for the Angels, B. Miller (3.99) for the Mariners. Dome — no weather impact. ParlayLab grades this matchup against the FanDuel line; the full pick selections unlock with Pro.

Away

Los Angeles Angels

Record
59-95
L10
4-6
RPG
4.02
OPS
.679

Probable starter

R. Detmers (3.36)

13 prior starts vs this opponent · 5.47 ERA

Home

Seattle Mariners

Record
72-82
L10
4-6
RPG
4.05
OPS
.690

Probable starter

B. Miller (3.99)

7 prior starts vs this opponent · 3.13 ERA

Matchup context

10:10 PM ET

Weather
Dome
Wind
—
Rain
—
Diff
-1.5

Projected score

LAA 2.4 — 2.6 SEA

Lines & ParlayLab picks

Moneyline · FanDuel

LAA+112

SEA-132

ParlayLab pick

— · edge —

Pro

Run line · FanDuel

LAA+1.5 (-220)

SEA-1.5 (+180)

ParlayLab pick

— · edge —

Pro

Total · FanDuel

O6.5 (-138)

U6.5 (+112)

ParlayLab pick

— · edge —

Pro

How ParlayLab grades this matchup

ParlayLab's methodology engine projects each MLB game with a market-blended model combining team offense (season + L14 rolling RPG and OPS), starting pitcher form (ERA, WHIP, K%, home/road splits), ballpark factors (per-handedness HR and run multipliers), weather (wind direction relative to center field, temperature, precipitation), bullpen fatigue, and Statcast contact quality. Outputs are a moneyline, run-line, and total projection — each graded HIGH / MED / LOW confidence based on edge versus the FanDuel line.

Free users see the top picks for each market plus the full matchup context shown above. The actual selections (which side to bet ML, RL, total) unlock with Pro. You're charged when you subscribe — cancel anytime.